张瑞福

　　教育经历:

　　1994.9-1998.6 山东莱阳农学院，农学系，农学学士

　　1998.9-2004.4 南京农业大学微生物学系，硕博连读，理学博士

　　工作经历:

　　2000/07-2002/07 哈尔滨工业大学市政环境工程学院，讲师

　　2004.6-2006.6 香港大学生物系， 博士后

　　2006.6-2008.9 美国德州农工大学植物病理与微生物学系，博士后

　　2008.9-2010.5 美国加州大学戴维斯分校农业与生物工程系，博士后

　　2010.5-至今   南京农业大学资源与环境科学学院，教授，博导

　　2014.7-至今  中国农科院农业资源与农业区划研究所，研究员，博导

　　研究方向：

　　根际微生物与微生物肥料；农业有机废弃物资源化利用生物技术；微生物资源保藏管理

　　专家类别：

　　入选国家级人才

　　中国农业科学院农科英才创新型领军人才

　　职务：

　　中国农业微生物菌种保藏管理中心主任，农业部农业微生物资源收集保藏重点实验室主任，江苏省固体有机废弃物资源化高技术研究重点实验室副主任

　　社会任职：

　　SCI 杂志International Biodeterioration & Biodegradation 编委

　　SCI 杂志Journal of Integrative Agriculture 编委

　　《微生物学杂志》编委

　　中国微生物学会常务理事

　　中国微生物学会微生物资源专委会主任

　　中国微生物学会农业微生物专委会委员

　　中国土壤学会理事

　　中国土壤学会土壤生物与生化专委会委员

　　中国植物营养与肥料学会生物与有机肥专委会副主任委员

　　中国植物营养与肥料学会植物营养生物学专委会委员

　　第七届农业部肥料评审登记委员会委员

　　第二届农业部耕地质量建设与管理专家指导组专家

　　承担科研项目情况：

　　国家微生物资源共享服务平台运行补助项目，科技部科技基础条件平台项目，2000-2200万/年，主持

　　“根际益生菌SQR9特异基因岛合成新型天然活性物质分析及其参与生物膜形成的自噬作用机制”，31870096，国家自然科学基金面上项目，59万，2019.1-2022.12. 主持。

　　“两组分系统ResD/E调控根际促生菌解淀粉芽孢杆菌SQR9根际定殖的分子机理研究”，31572214，国家自然科学基金面上项目，75.8万，2016.1-2019.12. 主持。

　　“根际有益菌在作物根表形成生物膜的机理模型与调控研究”，31330069，国家自然科学基金重点项目，312万，2014.1-2018.12. 参加。

　　“根际促生菌Bacillus amyloliquefaciens SQR9与植物根系分泌物互作的分子机理研究”，41271271，国家自然科学基金面上项目，75万，2013.1-2016.12. 主持。

　　“新型农业微生物肥效制剂的创制”，2013AA102802，科技部863项目，827万，2013.1-2017.12，主持。

　　“生防菌Bacillus amyloliquefaciens SQR9在植株根表原位条件下形成生物膜的蛋白组变化研究”，20110097110002，教育部博士点博导基金，12万，2012.1-2014.12，主持。

　　“微生物有机肥产业发展中的关键技术研究”，2011BAD11B03，科技部科技支撑计划，255万，2011.1-2015.12，课题主持。

　　获奖及荣誉：

　　中国自然资源学会青年科技奖，张瑞福,2013， 中国自然资源学会。

　　教育部科技进步一等奖，沈其荣,徐阳春,杨帆,杨兴明,薛智勇,陆建明,徐茂,李荣,赵永志,黄启为,张瑞福,余光辉,冉炜,李荣,沈标， 2013，有机肥作用机制和产业化关键技术研究与推广，教育部。

　　国家科技进步二等奖，沈其荣,徐阳春,杨帆,杨兴明,薛智勇,陆建明,徐茂,李荣,赵永志,黄启为,张瑞福,余光辉,冉炜,李荣,沈标， 2015，有机肥作用机制和产业化关键技术研究与推广，国务院。

　　农业部中华农业科技奖优秀创新团队奖，沈其荣，徐阳春，张瑞福，邹建文，杨兴明，黄启为，冉炜，郭世伟，余光辉，沈标，2015，有机肥和土壤微生物创新团队，农业部。

　　大北农科技奖，沈其荣，黄启为，李荣，刘东阳，张建，蔡枫，缪有志，张瑞福，凌宁，徐阳春，冉炜，陈巍，王其传，谭石勇，陆建明 2018，利用秸秆和废弃动物蛋白制造木霉固体菌种及木霉全元生物有机肥，大北农集团

　　国家科技进步二等奖，李顺鹏，崔中利，沈标，何健，杨新民，王新华，张瑞福，蒋建东，洪青， 2005，农药残留微生物降解技术的研究与应用，国务院。

　　全国农牧渔业丰收三等奖，李顺鹏，崔中利，沈标，何健，顾向阳，张瑞福，蒋建东，王新华，傅立斌，荆留民，刘军，洪青，陈立伟，房金钺， 2004， 农药残留微生物降解技术的研究与应用，农业部。

　　代表论著：

　　发表SCI论文80多篇，论文被SCI论文引用1200多次，近五年发表的第一个通讯作者SCI论文如下：

　　Xun W, Xiong W, Ren Y, Yan R, Lin D, Li W, Miao Y, Zhang G, Cui Z, Xin X* and Zhang R* 2018. Grazing drives soil productivity by regulating soil microbial community and organic carbon turnover in meadow steppes. Microbiome（Accepted）(IF5="11.0)

　　Zhang R, Vivanco MJ, and Shen Q*, 2017. The unseen rhizosphere root-soil-microbe interactions for crop production. Current Opinion in Microbiology 37:8-14.

　　Xun W, Zhao J, Xue C, Zhang G, Ran W, Wang B, Shen Q and Zhang R* 2016. Significant alteration of soil bacterial communities and organic carbon decomposition by different long-term fertilization management conditions of extremely low-productivity arable soil in South China. Environmental Microbiology 18:1907-1917.

　　Miao Y, Li P, Li G, Liu D, Druzhinina IS, Kubicek CP, Shen Q and Zhang R*. 2017 Two degradation strategies for overcoming the recalcitrance of natural lignocellulosic xylan by polysaccharides-binding GH10 and GH11 xylanases of filamentous fungi Environmental Microbiology 19:1054-1064.

　　Xun W, Huang T, Zhao J, Ran W, Wang B, Shen Q and Zhang R* 2015. Environmental conditions rather than microbial inoculum composition determine the bacterial community, microbial biomass and enzyme activity of reconstructed soil microbial communities. Soil Biology & Biochemistry 90:10-18.

　　Sun L†, Xun W†, Huang T, Zhang G, Gao J, Ran W, Li D, Shen Q and Zhang R* 2016. Alteration of the soil bacterial community during the parent materials maturation driven by different fertilizations Soil Biology & Biochemistry 96:207-215.

　　Feng H, Zhang N, Du W, Zhang H, Liu Y, Fu X, Shao J, Zhang G, Shen Q and Zhang R* 2018. Identification of chemotaxis compounds in root exudates and their sensing chemoreceptors in plant growth-promoting rhizobacteria Bacillus amyloliquefaciens SQR9. Molecular Plant-Microbe Interactions (Published online, doi: 10.1094/MPMI-01-18-0003-R)

　　Wu G†, Liu Y†, Xu Y, Zhang G, Shen Q and Zhang R* 2018. Exploring elicitors of beneficial rhizobacterium Bacillus amyloliquefaciens SQR9 to induce plant systemic resistance and their interactions with the signaling pathways Molecular Plant-Microbe Interactions 31(5):560-567.

　　Chen L†, Liu Y†, Wu G, Zhang N, Shen Q and Zhang R* 2017. Beneficial rhizobacterium Bacillus amyloliquefaciens SQR9 induces plant salt tolerance through spermidine production. Molecular Plant-Microbe Interactions 30:423-432.

　　Liu Y, Chen L, Feng H, Xu Y, Li Z, Wu G, Zhang N, Zhang G, Shen Q and Zhang R* 2017. Identification of root secreted compounds involved in the communication between soil-borne pathogen-cucumber-Bacillus amyloliquefaciens SQR9. Molecular Plant-Microbe Interactions 30:53-62.

　　Liu Y, Chen L, Zhang N, Li Z, Zhang G, Xu Y, Shen Q and Zhang R* 2016. Plant-microbe communication enhances auxin biosynthesis by a root-associated plant beneficial bacterium Bacillus amyloliquefaciens SQR9. Molecular Plant-Microbe Interactions 29:324-330.

　　Badri DV†，Chaparro JM†，Zhang R* , Shen Q，Vivanco JM*. 2013. Application of natural blends of phytochemicals derived from the root exudates of Arabidopsis to the soil reveal that phenolic related compounds predominantly modulate the soil microbiome. Journal of Biological Chemistry 288:4502-4512 (Co-corresponding author).

　　Qiu M, Xu Z, Li X, Li Q, Zhang N, Shen Q and Zhang R* 2014. Comparative proteomics analysis of Bacillus amyloliquefaciens SQR9 revealed the key proteins involved in in situ root colonization. Journal of Proteome Research 13:5581-5591.

　　Zhou X, Zhang N, Xia L, Li Q, Shao J, Shen Q and Zhang R* 2018. ResDE two-component regulatory system mediates oxygen limitation-induced biofilm formation of Bacillus Applied and Environmental Microbiology 84(8):e02744-17

　　Xu Z†, Zhang R†, Wang D, Qiu M, Feng H, Zhang N and Shen Q*. 2014. Enhanced control of cucumber wilt disease by Bacillus amyloliquefaciens SQR9 by altering the regulation of its DegU phosphorylation. Applied and Environmental Microbiology 80:2941-2950. (Co-First author)

　　Xu Z, Shao J, Li B, Yan X, Shen Q and Zhang R*. 2013. Contribution of Bacillomycin D in Bacillus amyloliquefaciens SQR9 to antifungal activity and biofilm formation Applied and Environmental Microbiology 79:808-815.

　　Zhang N†, Yang D†, Wang D, Miao Y, Shao J, Zhou X, Xu Z, Li Q, Feng H, Li S, Shen Q* and Zhang R* 2015. Whole transcriptomic analysis of the plant beneficial rhizobacterium Bacillus amyloliquefaciens SQR9 during enhanced biofilm formation regulated by maize root exudates. BMC Genomics 16:685

　　Miao Y, Liu D, Li G, Li P, Xu Y, Shen Q and Zhang R*. 2015 Genome wide transcriptomic analysis of a superior biomass degrading strain of Aspergillus fumigatus revealed the active lignocelluloses degrading genes. BMC Genomics 16:459.

　　Shao J, Li S, Zhang N, Cui X, Zhou X, Zhang G, Shen Q and Zhang R* 2015. Analysis and cloning of the synthetic pathway of the phytohormone indole-3-acetic acid in the plant-beneficial Bacillus amyloliquefaciens SQR9 Microbial Cell Factories 14:130.

　　Sun L, Gao J, Huang T, Kendall JR, Shen Q and Zhang R* 2015. Parental material and cultivation determine soil bacterial community structure and fertility. FEMS Microbiology Ecology 91:1-10.

　　Xun W, Li W, Huang T, Ren Y, Xiong W, Miao Y, Ran W, Li D, Shen Q and Zhang R* 2018. Long-term agronomic practices alter the composition of asymbiotic diazotrophic bacterial community and their nitrogen fixation genes in an acidic red soil. Biology and Fertility of Soils  54(3):329-339

　　Qiu M, Li S, Zhou X, Cui X, Vivanco JM*, Shen Q and Zhang R* 2014. De-coupling root-microbiome association followed by antagonist inoculation improves rhizosphere soil suppressiveness. Biology and Fertility of Soils 50:217-224.

　　Shao J, Xu Z, Zhang N, Shen Q and Zhang R* 2015. Contribution of indole-3-acetic acid in the plant growth promotion by the rhizospheric strain Bacillus amyloliquefaciens SQR9. Biology and Fertility of Soils 51(3):321-330.

　　Weng J†, Wang Y†, Li J, Shen Q and Zhang R*. 2013. Enhancing root colonization and biocontrol activity of Bacillus amyloliquefaciens SQR9 by abrB gene disruption Applied Microbiology & Biotechnology 97:8823-8830.

　　Li S†, Zhang R†, Wang Y, Zhang N, Qiu M, Shen B, Yin X, Shen Q*. 2013. Promoter analysis and transcription regulation of fus gene cluster responsible for fusaricidin synthesis of Paenibacillus polymyxa SQR-21 Applied Microbiology & Biotechnology 97:9479-9489.

　　Zhang N, Wang D, Liu Y, Li S, Shen Q and Zhang R* 2014. Effects of different plant root exudates and their organic acid components on chemotaxis, biofilm formation and colonization by beneficial rhizosphere-associated bacterial strains Plant Soil 374:689-700.

　　Xun W, Huang T, Li W, Ren Y, Xiong W, Ran W, Li D, Shen Q and Zhang R* 2017. Alteration of soil bacterial interaction networks driven by different long-term fertilization management practices in the red soil of South China. Applied Soil Ecology 120:128-134.

　　Xun W, Xiong W, Huang T, Ran W, Li D, Shen Q, Li Q and Zhang R* 2016. Swine manure and quicklime have different impacts on chemical properties and composition of bacterial communities of an acidic soil. Applied Soil Ecology 100:38-44.

　　Chen L, Xun W, Sun L, Zhang N, Shen Q and Zhang R*. 2014. Effect of different long-term fertilization regimes on soil viral community in a red soil of southern China. European Journal of Soil Biology 62:121-126.

　　Zhang N†, Yang D†, Kendall JR, Miao Y, Zhang G, Druzhinina, IS, Kubicek CP, Shen Q and Zhang R* 2016. Comparative genomic analysis of Bacillus amyloliquefaciens and Bacillus subtilis reveals evolutional traits for adaptation to plant-associated habitats. Frontiers in Microbiology 7:2039.

　　Liu Y†, Yang D†, Zhang N, Chen L, Cui Z, Shen Q, Zhang R* 2016. Characterization of uncultured genome fragment from soil metagenomic library exposed rare mismatch of internal tetranucleotide frequency. Frontiers in Microbiology 7:2081.

　　Li B, Li Q, Xu Z, Zhang N, Shen Q and Zhang R* 2014. Responses of beneficial Bacillus amyloliquefaciens SQR9 to different soilborne fungal pathogens through the alteration of antifungal compounds production Frontiers in Microbiology 5:636

　　Zhao J†, Zhang R†, Xue C, Xun W, Sun L and Shen Q*. 2014. Pyrosequencing reveals contrasting soil bacterial diversity and community structure in two main winter wheat growing areas of China. Microbial Ecology 67:443-453 (Co-First author).

　　Zhao J, Ni T, Li Y, Xiong W, Ran W, Shen B, Shen Q and Zhang R*. 2014. Responses of bacterial communities in arable soils under a rice-wheat cropping system to different fertilizer regimes and sampling time Plos One 9: e85301.

　　Liu Y, Zhang N, Qiu M, Feng H, Vivanco JM, Shen Q and Zhang R*. 2014. Enhanced rhizosphere colonization of beneficial Bacillus amyloliquefaciens SQR9 by pathogen infection FEMS Microbiology Letters 353:49-56.

　　Miao Y, Li J, Xiao Z, Shen Q and Zhang R* 2015. Characterization and identification of thermostable xylanolytic enzymes from Aspergillus fumigatus Z5. BMC Microbiology 15:126.

　　Xun W, Xu Z, Li W, Ren Y, Huang T, Ran W, Wang B, Shen Q and Zhang R* 2016. Long-term organic-inorganic fertilization ensures great soil productivity and bacterial diversity after natural-to-agricultural ecosystem conversion Journal of Microbiology 54:611-617.

　　Njeri KV, Chen L, Liu Y, Raza W, Zhang N, Mungai LK, Shen Q and Zhang R* 2016. Characterization of extracellular polymeric substances of Bacillus amyloliquefaciens SQR9 induced by root exudates of cucumber. Journal of Basic Microbiology 56:1183–1193.

　　Zhang R, Xu C, Shen Q, Kusuga T, Wu W, Szewczyk E,Ma D and Fan Z*. 2013. Characterization of two cellobiose dehydrogenases and comparision of their contributions to total activity in Neurospora crassa. International Biodeterioration & Biodegradation 82:24-32.